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Office 60 of Istanbul's main bus terminal (Büyük Otogar) is for buses to Kütahya, and also Afyon, Alanya, Antalya, Isparta (for Egirdir), and Kemer, the resort town southwest of Antalya, run by the Kütahyalilar company.
The Öztur company runs buses from Istanbul to Hatay (Antakya and Iskenderun).
Alphabetical List of Destinations
Full List of Offices/Perons & Companies
Istanbul Bus Terminal (Otogar) Homepage