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The Kâmil Koç bus company operating from Offices 144, 145 and 146 at Istanbul's Büyük Otogar (main bus terminal) is one of Turkey's oldest and largest, running buses from Istanbul to these destinations.
Telephone (212) 444 0562; or (212) 658 2000 at Istanbul's Büyük Otogar.
Here's more information on Kâmil Koç buses.
Turkey's Best Bus Companies
Bus Travel in Turkey
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Alphabetical List of Destinations from Istanbul
Full List of Offices/Perons & Companies
Istanbul Bus Terminal (Otogar) Homepage